ibiomagazine2011.1.8---Cynthia Kenyon:控制衰老遺傳

ibiomagazine2011.1.8---Cynthia Kenyon:控制衰老遺傳

Cynthia Kenyon: A Genetic Control Circuit for Aging
ibiomagazine 於 2011-01-08 上傳

http://www.ibiomagazine.org/index.php/issues/december-2010-issue/cynthia-kenyon
In the early 1990s, most scientists did not think that aging was subject to active regulation by the genes. Exciting results from Dr. Kenyon's lab, however, showed that a single mutation in the daf-2 gene caused the tiny roundworm C. elegans to live twice as long as normal. This gene encodes a hormone receptor that regulates lifespan not only in worms, but in flies, mammals and possibly humans as well.

辛西婭凱尼恩：一個衰老遺傳控制電路
biomagazine於2011-01-08上傳

http://www.ibiomagazine.org/index.php/issues/december-2010-issue/cynthia-kenyon
在20世紀 90年代初，大多數科學家並不認為，老化是受基因的主動調控。然而，令人振奮的結果凱尼恩博士的實驗室表明，在DAF - 2基因的單基因突變引起的微小的蛔蟲線蟲生活只要正常的兩倍。該基因編碼的一種激素受體調節不僅在蠕蟲，但在蒼蠅，哺乳動物和人類的壽命