ibioseminars2011.10.8---Sangeeta Bhatia:微型肝臟組織工程替換

ibioseminars2011.10.8---Sangeeta Bhatia:微型肝臟組織工程替換

Sangeeta Bhatia Part 1: Engineering Tissue Replacements
ibioseminars 於 2011-10-08 上傳

http://www.ibioseminars.org/lectures/cell-bio-a-med/sangeeta-bhatia.html

The concept of engineering tissues that are part cell and part synthetic material was proposed nearly 20 years ago. Bhatia explains why one would choose to use an engineered tissue and the challenges of engineering a tissue that reproduces the micro-architecture of tissue in vivo. She goes on to describe how the ingredients and the methods of fabrication of a hybrid tissue are chosen.

交給 Sangeeta巴蒂亞第1部分：工程組織替換
ibioseminars於2011年10月8日上傳

http://www.ibioseminars.org/lectures/cell-bio-a-med/sangeeta-bhatia.html

一部分細胞和部分合成材料工程組織的概念，提出了近20年前。巴蒂亞解釋為什麼人們會選擇使用一個精心設計的組織和工程的挑戰，一個組織，再現體內組織的微架構。她接著描述如何選擇成分和混合組織的製造方法
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Sangeeta Bhatia Part 2: Microscale Liver Tissue Engineering
ibioseminars 於 2011-10-08 上傳

http://www.ibioseminars.org/lectures/cell-bio-a-med/sangeeta-bhatia/sangeeta-...

In the second part of her talk, Bhatia tells us about research from her lab and others to develop an implantable, engineered liver. She explains the challenges of co-culturing hepatocytes and the supporting cells necessary to keep the hepatocytes functional. Her lab has successfully engineered microscale human livers that are showing promise as a mechanism to identify drugs that are toxic to the liver and to study viruses and parasites that attack the liver.

交給 Sangeeta巴蒂亞第2部分：微型肝臟組織工程
ibioseminars於2011年10月8日上傳

http://www.ibioseminars.org/lectures/cell-bio-a-med/sangeeta-bhatia/sangeeta-...

在她的談話中的第二部分，巴蒂亞我們講述了她的實驗室和其他研究開發一種植入，工程肝。她解釋共培養肝細胞的挑戰和必要保持肝功能的支持細胞。她的實驗室已成功地設計了微型人類肝臟，作為一種機制，以確定對肝臟有毒的藥物，並研究病毒和寄生蟲，攻擊肝臟的承諾。